Amnio FRT / Amnio F

Amnio FRTTM is a flowable tissue allograft derived from human amniotic fluid. Amnio FTM is a cryopreserved allograft derived from human amniotic fluid.
The Amniotic fluid-derived cells are obtained from the placental tissue of donors at the time of a live, full-term elective Cesarean birth.

Wound Healing Components

Amnio FTM is rich with the basic components necessary for tissue repair and wound healing. It contains collagen substrates, growth factors, amino acids, carbohydrates, and cytokines.

The wound healing elements found in Amnio FTM are known to facilitate migration and proliferation of cells to the site of injury and construct a natural scaffold on which new tissue growth can occur.(1-7)*

Chorion-Free Allograft

Alliance Spine allografts do not contain chorion, which may reduce the risk of an adverse reaction in the patient.

Tissue Safety

Placental donors go through a rigorous pre- screening qualification and are tested according to FDA guidelines for infectious disease.
Collection of the donor tissue is performed during a planned Cesarean section and processed in accordance with the standards and guidelines established by the American Association of Tissue Banks (AATB).

Benefits of amniotic fluid may include

  • A safe, natural covering for wounds
  • Inhibiting influence on Inflammation
  • Intended for topical application as a covering over wounds.
  • Birth tissues are recovered during planned Cesarean sections and processed aseptically in a manner to preserve the graft’s inherent properties.

Handling & Storage Guidelines

Amnio FTM and Amnio FRTTM comes in an easy to use, liquid format. It is a non-invasive, surgical or in-office treatment applied topically or implanted at the area of concern.

Amnio FTM.
  • Amnio FTM is cryopreserved for safe, long-term storage and ease of handling
  • Store at -70 degrees C or colder. Thaw only prior to use.
  • Allow product to thaw by standing at room temperature and apply directly to the injury, wound, or area of inflammation.
  • See Instructions for Use for a more detailed description.
  • Store at ambient temperature (59-86°F/15-30°C) until ready for use
  • Provided as a sterile, ready to use, flowable graft with no thawing or preparation required
  • Apply directly to the wound or area of inflammation
  • See Instructions for Use for more details


Amnio F(Cryopreserved)

AVI-5200 Amnio FTM Liquid Amnion 2.0mL

Amnio FRT

PRO-04-005 Amnio FRT Liquid Amnion 0.5mL
PRO-04-001 Amnio FRT Liquid Amnion 1.0mL
PRO-04-002 Amnio FRT Liquid Amnion 2.0mL


  1. Nyman E, Huss F, Nyman T, Junker], Kratz G. (2013 Apr) Hyaluronic acid, an important factor in the wound healing properties of amniotic fluid: in vitro studies of re-epithelialisation in human skin wounds. J Plast Surg Hand Surg. 47(2):89-92
  2. Adzick NS, Lorenz HP (1994 Jul Cells, matrix, growth factors, and the surgeon. The biology of scarless fetal wound repair. Annals of Surgery.;220(1):10-18.
  3. Gao X, Devoe LD, Given KS. (1994 Aug) Effects of amniotic fluid on proteases: a possible role of amniotic fluid in fetal wound healing. Annals of Plastic Surgery. 33(2):128-134; discussion 134-135.
  4. Bo/at E, Kocamaz E, Kulahcilar Z, YilmazA, TopcuA, Ozdemir M, Coskun ME. (2013 Dec) Investigation of efficary of mitomycin-C, sodium hyaluronate and human amniotic fluid in preventing epidural fibrosis and adhesion using a rat laminectomy model. Asian Spine J 7(4):253-9.
  5. Cobanglu U, Kutlu N, Karacal N, Kosucu P (2005 Dec) Effect of human amniotic fluid on bone healing. J Surg Res. 129(2):283-1.
  6. Ozgenel GY, Filiz G, Ozcan M. (2004 Jul Effects of human amniotic fluid on cartilage regeneration from free perichondrial grafts in rabbits. Br J Plast Surg. 57(5):423-8.
  7. Rosner M, Hipatry K, S hanmugasundaram B, Lubec G, Hengstschlager M (2012 Jun) Amniotic Fluid Stem Cells: Future Perspectives. Stem Cells Int. 2012: 741810.

For more information view our Amnio F brochure